2024 Summer Intern - gRED Early Clinical Development, OMNI Clinical Science (roche)

Job Description

Department Summary

Genentech’s Research and Early Development (gRED) Early Clinical Development (ECD) organization is responsible for developing and executing early development clinical strategies and plans to provide proof-of-concept data with respect to safety, efficacy, and the utility of biomarkers for gRED new molecular entities.

Working with the Neuroscience group team (Postdoctoral Scientist and Group Medical Director), the intern will support a project focused on Alzheimer’s Disease (AD). In particular, the intern will use a harmonized quantification scale for tau PET data to delineate biological stages of AD.

Pathological tau, as measured by tau PET, is related to cognitive decline in Alzheimer’s disease, and the ability to biologically determine an individual’s disease stage can aid in the study of Alzheimer’s disease and the development of novel therapies. Although measures of tau PET using different PET radiotracers cannot be directly compared, conversion to a harmonized scale (CenTauR) enables comparisons across tracers. This project involves the extraction of CenTauR values from several AD imaging datasets and the conceptualization and implementation of staging methods for AD. Insights from these analyses will contribute to our understanding of Alzheimer’s disease and will inform the use of the harmonized scale in future clinical trials.

This internship position is located in South San Francisco, on site.

Key Responsibilities

• Opportunity to work with the Clinical Science Team Leaders/Clinical Scientists in Neuroscience group to analyze clinical trial results 

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• Present results at team meetings and at departmental meetings to the Genentech scientific community, as well as an opportunity to present to external audiences (conferences, publications)

• Ownership of challenging and impactful business-critical projects

• Work with some of the most talented people in the biotechnology industry

• Lead or participate in intern committees to design and coordinate program events and initiatives

• Professional & personal development curriculum throughout the program, including networking opportunities, workshops, and panel discussions

Program Highlights

• Intensive 12-weeks, full time (40 hours per week) paid internship.

• Program start dates are in May/June (Summer) 

• A stipend, based on location, will be provided to help alleviate costs associated with the internship. 

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are (Required) 

- Must be pursuing a PhD (enrolled student) in Biology, Neuroscience, Biochemistry, Computational Biology

Required skills: 

• Strong programming skills, experience processing and analyzing MRI and PET brain images, and coding in MATLAB, python, or R

• Experience working in complex matrixed (multi-disciplinary) setting(s)

• Experience working with the principles and techniques of data analysis and visualization, interpretation, and assessment of clinical relevance 

• Experience analyzing clinical or healthcare data preferred

• Interest or experience in neurosciences and neurodegenerative diseases a plus

Preferred Qualifications

• Has impeccable ethics.  Demonstrates, or proven abilities to demonstrate, gRED values. 

• Outstanding attention to detail. 

• Excellent project management skills: can prioritize multiple tasks and goals and deliver them in a timely, on-target and high-quality manner

• Strong interpersonal, verbal communication and influencing skills: can influence without authority and is willing to cultivate relationships with key partners and stakeholders, both internally and externally 

• Outstanding written communication skills 

• Strong presentation skills: effective at summarizing and presenting the key considerations and decision-points 

• Excellent teamwork skills: knows how to complete deliverables by working effectively with colleagues; can effectively drive discussions and decisions toward desired end results 

Relocation benefits are not available for this job posting. 

The expected salary range for this position based on the primary location for this position in California is $22.00 - $55.00 per hour.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits. 

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.